VEGFR-2-IN-60
VEGFR-2-IN-60 (compound 5c) is a potent VEGFR-2 inhibitor with an IC50 of 1.07 nM. VEGFR-2-IN-60 exhibits cytotoxic activity against HCC1806, Hela, and A549 cell lines[1].
Product Specifications
UNSPSC
12352005
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC1=CC2=C(C(OC3=CC(OC(C(/C=C/C4=CNC5=C4C=CC=C5)=O)=C6)=C6C=C3)=NC=N2)C=C1OC
Molecular Formula
C29H21N3O5
Molecular Weight
491.49
References & Citations
[1]Liu Y, et al. Benzofuran-Chalcone Derivatives as VEGFR-2 Inhibitors: Synthesis and Anticancer Evaluation. Chem Biodivers. 2024 Nov 15:e202401991.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Curated Selection
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