IKZF-IN-1

IKZF-IN-1 (Compound I) is the molecular glue, that degrades ikaros zinc finger family (IKZF) IKZF 1/2/3/4, and can be used as an immunomodulator in research of cancer and viral infections[1].

Product Specifications

UNSPSC

12352005

Target

IKZF Family; Molecular Glues

Related Pathways

Immunology/Inflammation; PROTAC

Field of Research

Cancer; Infection

Smiles

O=C1N(C2C(NC(CC2)=O)=O)CC3=C(F)C(C4=CC=C(CN5CC6(CCCOC6)C5)C(N)=N4)=CC=C31

Molecular Formula

C26H28FN5O4

Molecular Weight

493.53

References & Citations

[1]CHERNEY EC, et al., Synthesis of spirocyclic substituted oxoisoindolinyl piperidine-2,6-dione compound for treatment of viral infections and proliferative disorders, such as cancer. WO2024254227