1,2,3,7,8,9-Hexachlorodibenzofuran

1,2,3,7,8,9-Hexachlorodibenzofuran is a polychlorinated dibenzofuran homologue. 1,2,3,7,8,9-Hexachlorodibenzofuran can interact with AhR. 1,2,3,7,8, 9-hexachlorodibenzofuran is highly toxic, teratogenic, carcinogenic and mutagenic[1][2].

Product Specifications

CAS Number

[72918-21-9]

UNSPSC

12352101

Target

Aryl Hydrocarbon Receptor

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Smiles

ClC1=CC2=C(C(Cl)=C1Cl)C3=C(Cl)C(Cl)=C(Cl)C=C3O2

Molecular Formula

C12H2Cl6O

Molecular Weight

374.86

References & Citations

[1]Ghorbanzadeh M, et al. In vitro and in silico derived relative effect potencies of ah-receptor-mediated effects by PCDD/Fs and PCBs in rat, mouse, and guinea pig CALUX cell lines. Chem Res Toxicol. 2014 Jul 21;27 (7) :1120-32.|[2]Xia X, et al. Polycyclic Aromatic Hydrocarbons and Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans in Microliter Samples of Human Serum as Exposure Indicators. J Occup Environ Med. 2016 Aug;58 (8 Suppl 1) :S72-9.