GB2095
GB2095 is an orally active and selective galectin-3 inhibitor. GB2095 shows superior selectivity for both human (KD = 0.036 μM) and mouse galectin-3 (KD = 0.35 μM) over other galectins (such as h-Gal-1/4N/4C/8N/8C/9N/9C and m-galectin-1) . GB2095 inhibits tumor growth in syngeneic mouse models of breast and melanoma cancers. GB2095 can be used for breast and melanoma cancer research[1].
Product Specifications
CAS Number
[2574415-75-9]
UNSPSC
12352005
Target
Galectin
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](N2C=C(C3=CC(F)=C(C(F)=C3)Cl)C=N2)[C@H]([C@H](O[C@@H]1SC4=CN=CC(Br)=C4)CO)O
Molecular Formula
C20H17BrClF2N3O4S
Molecular Weight
548.79
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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