CDK-IN-16
CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC50 of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC50 of CDK-IN-16 against the AGS cell line is 3.5 μM[1].
Product Specifications
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
OC1=CC=C(C2=C3CCC4=CC=CC=C4C3=NC(C5=CC=CN=C5)=N2)C=C1
Molecular Formula
C23H17N3O
Molecular Weight
351.40
References & Citations
[1]Saravanakumar N, et al. Novel Fused Pyrimidines as Potent Cyclin-Dependent Kinases Inhibitor for Gastric Adenocarcinoma: Combined In Vitro, In Silico Anticancer Studies. Chem Biol Drug Des. 2024 Nov;104 (5) :e70013.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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