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CDK-IN-16

CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC50 of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC50 of CDK-IN-16 against the AGS cell line is 3.5 μM[1].

Product Specifications

UNSPSC

12352005

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

OC1=CC=C(C2=C3CCC4=CC=CC=C4C3=NC(C5=CC=CN=C5)=N2)C=C1

Molecular Formula

C23H17N3O

Molecular Weight

351.40

References & Citations

[1]Saravanakumar N, et al. Novel Fused Pyrimidines as Potent Cyclin-Dependent Kinases Inhibitor for Gastric Adenocarcinoma: Combined In Vitro, In Silico Anticancer Studies. Chem Biol Drug Des. 2024 Nov;104 (5) :e70013.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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