MAT2A-IN-20
MAT2A-IN-20 (Compound A49) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 ≤50 nM. MAT2A-IN-20 inhibits human UGT1A1 with an IC50 of 28.45 μM. MAT2A-IN-20 exhibits antitumor in mouse models[1].
Product Specifications
CAS Number
3018834-98-2
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C1C(C2=CC3=C(N=C(C(C)(C)O)N3C)C=C2)=NC4=C(N1C5=CC=C(C=C5)OC(F)F)N=C(OCC)N=C4
Molecular Formula
C26H24F2N6O4
Molecular Weight
522.50
References & Citations
[1]Wang K, et al., Pyrimido nitrogen-containing six-membered aromatic heterocyclic compound and application thereof. CN115504980A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![APC Mouse IgG2b, κ Isotype Control[MPC-11]](https://cdn.genprice.uk/products/763/68dd14b2061270361e7d4244/imageurl/e-ab-f09812e.webp)
E-AB-F09812E-01 20 Tests
APC Mouse IgG2b, κ Isotype Control[MPC-11]
Sign In for Pricing
View Details E-AB-F09812E-02 100 Tests
APC Mouse IgG2b, κ Isotype Control[MPC-11]
Sign In for Pricing
View Details E-AB-F09812E-03 2x 100 Tests
APC Mouse IgG2b, κ Isotype Control[MPC-11]
Sign In for Pricing
View Details 