GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for GABA-A receptor with a pKi of 7.27. GABA-A Receptor Ligand-1 reduces mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration. GABA-A Receptor Ligand-1 exhibits neuroprotective efficacy in rats ischemic stroke models[1].
Product Specifications
CAS Number
3076335-23-1
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC(C=C1)=CN2C1=NC(C3=CC=C(C=C3)F)=C2CC(N4CCCC4)=O
Molecular Formula
C20H20FN3O
Molecular Weight
337.39
References & Citations
[1]Mordyl B, et al., Preferential Synaptic Type of GABA-A Receptor Ligands Enhancing Neuronal Survival and Facilitating Functional Recovery After Ischemic Stroke. J Med Chem. 2024 Dec 26;67 (24) :21859-21889.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![CEACAM1 Mouse Monoclonal Antibody [Clone ID: B3]](https://cdn.genprice.uk/products/937/68dd189c061270361e8fc9f1/imageurl/am26012pu-n.webp)
AM26012PU-N 100 µg
CEACAM1 Mouse Monoclonal Antibody [Clone ID: B3]
Sign In for Pricing
View Details 
PKSH033483-01 10 µg
Recombinant Human TROP2/TACSTD2 Protein (Fc Tag)
Sign In for Pricing
View Details PKSH033483-02 50 µg
Recombinant Human TROP2/TACSTD2 Protein (Fc Tag)
Sign In for Pricing
View Details 
BNC880868-500 1x 500 µL
Golgi Complex (AE-6), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
RD-FOXO1-Ra-01 96 Tests
Rat Forkhead Box Protein O1 (FOXO1) ELISA Kit
Sign In for Pricing
View Details