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Fluc-IN-1

Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay) [1].

Product Specifications

UNSPSC

12352005

Target

Wnt

Related Pathways

Stem Cell/Wnt

Field of Research

Cancer

Purity

98.44

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C)C=C1C)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O

Molecular Formula

C26H23N3O2S2

Molecular Weight

473.61

References & Citations

[1]Kinsolving J, et al., A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor. J Med Chem. 2024 Dec 26;67 (24) :22332-22341.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-170496/Fluc-IN-1-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[2940242-10-2]

Available Sizes

Curated Selection

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