Fluc-IN-1
Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay) [1].
Product Specifications
CAS Number
2940242-10-2
UNSPSC
12352005
Target
Wnt
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Purity
98.44
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C)C=C1C)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
Molecular Formula
C26H23N3O2S2
Molecular Weight
473.61
References & Citations
[1]Kinsolving J, et al., A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor. J Med Chem. 2024 Dec 26;67 (24) :22332-22341.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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