Antiviral agent 66
Antiviral agent 66 (Compound 60) is the inhibitor for Filovirus, that inhibits pseudotyped virus of Ebola, Marburg, Zaire, Sudan, Bundibugyo, Reston and Tai Forest with EC50s of 0.16, 2.24, 0.16, 0.89, 0.21, 0.21 and 0.11 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Filovirus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=NC=C(C(NC2=CC=C(N3CCC4(CCC4)CC3)C(C(F)(F)F)=C2)=O)C=C1)N5C[C@H]6OC[C@@H]5C6
Molecular Formula
C27H29F3N4O3
Molecular Weight
514.54
References & Citations
[1]Argade MD, et al., Guardians at the Gate: Optimization of Small Molecule Entry Inhibitors of Ebola and Marburg Viruses. J Med Chem. 2025 Jan 9;68 (1) :135-155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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