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Antiviral agent 66

Antiviral agent 66 (Compound 60) is the inhibitor for Filovirus, that inhibits pseudotyped virus of Ebola, Marburg, Zaire, Sudan, Bundibugyo, Reston and Tai Forest with EC50s of 0.16, 2.24, 0.16, 0.89, 0.21, 0.21 and 0.11 μM, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Filovirus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C1=NC=C(C(NC2=CC=C(N3CCC4(CCC4)CC3)C(C(F)(F)F)=C2)=O)C=C1)N5C[C@H]6OC[C@@H]5C6

Molecular Formula

C27H29F3N4O3

Molecular Weight

514.54

References & Citations

[1]Argade MD, et al., Guardians at the Gate: Optimization of Small Molecule Entry Inhibitors of Ebola and Marburg Viruses. J Med Chem. 2025 Jan 9;68 (1) :135-155.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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