MAO-B-IN-38

MAO-B-IN-38 (Compound 6b) is a reversible and competitive MAO-B inhibitor, with IC50 values of 0.03 and 21.46 µM for MAO-B and MAO-A, respectively. MAO-B-IN-38 can be used for the research of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases[1].

Product Specifications

UNSPSC

12352005

Target

Monoamine Oxidase

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

CCS(=O)(NC1=NN=C(C2=CC=C(N3CCSCC3)C(F)=C2)S1)=O

Molecular Formula

C14H17FN4O2S3

Molecular Weight

388.50

References & Citations

[1]Dhangar MS, et al. Optimizing Linezolid: Transforming It into a Selective MAO-B Inhibitor via a Toxicity-to-Activity Optimization Approach. ACS Med Chem Lett. 2024 Dec 16;16 (1) :40-50.