MAO-B-IN-38
MAO-B-IN-38 (Compound 6b) is a reversible and competitive MAO-B inhibitor, with IC50 values of 0.03 and 21.46 µM for MAO-B and MAO-A, respectively. MAO-B-IN-38 can be used for the research of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCS(=O)(NC1=NN=C(C2=CC=C(N3CCSCC3)C(F)=C2)S1)=O
Molecular Formula
C14H17FN4O2S3
Molecular Weight
388.50
References & Citations
[1]Dhangar MS, et al. Optimizing Linezolid: Transforming It into a Selective MAO-B Inhibitor via a Toxicity-to-Activity Optimization Approach. ACS Med Chem Lett. 2024 Dec 16;16 (1) :40-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Curated Selection
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