Antitumor agent-191
Antitumor agent-191 (Compound 7) exhibits antiviral activity against HSV-1 and HIV with EC50 of 0.03 μM and 0.81 μM. Antitumor agent-191 exhibits potential antitumor efficacy, that inhibits cancer cell HepG2, WI-38, Vero and MCF-7, with IC50s of 19.6, 39.3, 18.3 and 28 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
HIV; HSV
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
NC1=C(C2=NC(C3=CC=C(C4=CSC(C5=C(N)N6C(N=C5)=NC=N6)=N4)C=C3)=CS2)C=NC7=NC=NN17
Molecular Formula
C22H14N12S2
Molecular Weight
510.56
References & Citations
[1]Sefrji FO, et al., Synthetic approaches for novel fused pyrimidine derivatives: Design, structural characterization, antiviral, antitumor, and molecular docking evaluation. Heliyon. 2024 Dec 4;10 (24) :e40903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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