MDM2 ligand 4
MDM2 ligand 4 is the ligand for MDM2 that can be used for synthesis of PROTAC degrader KT-253.
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; MDM-2/p53
Related Pathways
Apoptosis; PROTAC
Field of Research
Cancer
Smiles
ClC1=CC2=C([C@]3(C4(CCCCC4)C[C@@H](C(N[C@H]5CC[C@H](C(O)=O)CC5)=O)[C@@H]3C6=C(F)C(Cl)=CC=C6)C(N2)=O)C=C1
Molecular Formula
C31H33Cl2FN2O4
Molecular Weight
587.51
References & Citations
[1]Chutake YK, et al., KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors. Mol Cancer Ther. 2024 Dec 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Integrin beta 3 Recombinant Rabbit Monoclonal Antibody [PSH09-27]](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81b89/imageurl/ha723085.webp)
HA723085 100 µL
Integrin beta 3 Recombinant Rabbit Monoclonal Antibody [PSH09-27]
Sign In for Pricing
View Details 