AR ligand-38
AR ligand-38 is the ligand for androgen receptor, that can be used for synthesis of PROTAC AR Degrader-9 (HY-170448) [1].
Product Specifications
UNSPSC
12352005
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Smiles
O=C(C1=CC=C(C=C1)C2CCN(CC2)C(OC(C)(C)C)=O)N[C@H]3CC[C@@H](CC3)OC4=CC(Cl)=C(C=C4)C#N
Molecular Formula
C30H36ClN3O4
Molecular Weight
538.08
References & Citations
[1]Mao X, et al., Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia. J Med Chem. 2024 Dec 26;67 (24) :22218-22244.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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