Neuraminidase-IN-23

Neuraminidase-IN-23 (33c) is a potent neuraminidase (NA) inhibitor against influenza virus, with IC50 values of 0.049 μM (H1N1), 0.26 μM (H3N2), 0.17 μM (H5N1), 0.013 μM (H5N8) and 0.74 μM (H5N1-H274Y), respectively[1].

Product Specifications

UNSPSC

12352005

Target

Influenza Virus

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Smiles

O=C(C1=C[C@H]([C@@H]([C@H](C1)NCC2=CC=C(C=C2Cl)OCC3=CC=CC(B(O)O)=C3)NC(C)=O)OC(CC)CC)O

Molecular Formula

C28H36BClN2O7

Molecular Weight

558.86

References & Citations

[1]Jiwei Zhang, et al. Elaborate Structural Modifications Yielding Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Potent Neuraminidase Inhibitors with Significantly Improved Broad-Spectrum Antiresistance Profiles. J Med Chem. 2024 Dec 26;67 (24) :22191-22217.