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NFh-NMe-2

NFh-NMe-2 is a photosensitizer, that interacts with nitroreductase, generates singlet oxygen in tumor cells, exhibits cytotoxicity in cancer cells, and induces apoptosis. NFh-NMe-2 exhibits antitumor efficacy in mouse models[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Photosensitizer

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC1(C(/C=C/C(CCC2)=C3C2=CC4=C(O3)C=C(NC)C=C4)=[N+](C5=CC=C6C(C=CC=C6)=C51)CC)C.[I-]

Molecular Formula

C32H33IN2O

Molecular Weight

588.52

References & Citations

[1]Zhao C, et al., An Activatable Heavy-Atom-Free Upconversion Photosensitizer for Targeted Imaging and Treatment of Tumors. J Med Chem. 2024 Dec 26;67 (24) :22322-22331.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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