NFh-NMe-2
NFh-NMe-2 is a photosensitizer, that interacts with nitroreductase, generates singlet oxygen in tumor cells, exhibits cytotoxicity in cancer cells, and induces apoptosis. NFh-NMe-2 exhibits antitumor efficacy in mouse models[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Photosensitizer
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1(C(/C=C/C(CCC2)=C3C2=CC4=C(O3)C=C(NC)C=C4)=[N+](C5=CC=C6C(C=CC=C6)=C51)CC)C.[I-]
Molecular Formula
C32H33IN2O
Molecular Weight
588.52
References & Citations
[1]Zhao C, et al., An Activatable Heavy-Atom-Free Upconversion Photosensitizer for Targeted Imaging and Treatment of Tumors. J Med Chem. 2024 Dec 26;67 (24) :22322-22331.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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