IPS-06061
IPS-06061 is an orally active molecule glue, that forms a ternary complex of CRBN-KRASG12D-IPS06061, and degrades KRAS G12D with a DC50 [1].
Product Specifications
CAS Number
3064065-83-1
UNSPSC
12352005
Target
Molecular Glues; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(OCC)[C@@H](N[C@H](C(C1=CC=CC=C1)=O)C)CCC2=CC=CC=C2
Molecular Formula
C21H25NO3
Molecular Weight
339.43
References & Citations
[1]Kang I, et al., COMPOUNDS TARGETING KRAS G12D MUTATIONS AND THEIR USES. WO2024241248
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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