IPS-06061
IPS-06061 is an orally active molecule glue, that forms a ternary complex of CRBN-KRASG12D-IPS06061, and degrades KRAS G12D with a DC50 [1].
Product Specifications
CAS Number
3064065-83-1
UNSPSC
12352005
Target
Molecular Glues; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(OCC)[C@@H](N[C@H](C(C1=CC=CC=C1)=O)C)CCC2=CC=CC=C2
Molecular Formula
C21H25NO3
Molecular Weight
339.43
References & Citations
[1]Kang I, et al., COMPOUNDS TARGETING KRAS G12D MUTATIONS AND THEIR USES. WO2024241248
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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