MAT2A-IN-16
MAT2A-IN-16 is a MAT2A inhibitor and inhibits cell proliferation of MTAP-/- HCT-116 cells (IC50: 20 nM) [1].
Product Specifications
CAS Number
[3025016-60-5]
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C1N=C2C3=C(CN2C4=CC5=CN(C)N=C5C=C4)C=C(Cl)C=C3N1C6=CC=CN=C6C
Molecular Formula
C23H17ClN6O
Molecular Weight
428.87
References & Citations
[1]Wang Kuanglei, et al. Tricyclic compounds and uses thereof. Patent. WO2024002024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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