EMD-95885
EMD-95885 is a selective NR2B-containing NMDA receptors antagonist with an IC50 of 3.9 nM. EMD-95885 does not interact with other sites on the NMDA receptor[1].
Product Specifications
CAS Number
[178165-43-0]
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
98.74
Smiles
O=C1OC2=CC(C(CCN3CCC(CC3)CC4=CC=C(C=C4)F)=O)=CC=C2N1
Molecular Formula
C22H23FN2O3
Molecular Weight
382.43
References & Citations
[1]Roger G, et al. Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors. Bioorg Med Chem. 2004 Jun 15;12 (12) :3229-37.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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