Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HDAC-IN-84

HDAC-IN-84 (compound 4d) is a potent HDAC inhibitor, with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8 and 26 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC11, respectively. HDAC-IN-84 effectively inhibits the proliferation of leukemia cells without causing toxicity[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; HDAC

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(C1=NC(C2=CC=C(OC)C=C2)=CS1)NOCCCCCC(NO)=O

Molecular Formula

C17H21N3O5S

Molecular Weight

379.43

References & Citations

[1]Fischer F, et.al. Deciphering the Therapeutic Potential of Novel Pentyloxyamide-Based Class I, IIb HDAC Inhibitors against Therapy-Resistant Leukemia. J Med Chem. 2024 Dec 12;67 (23) :21223-21250.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC11; HDAC2; HDAC3; HDAC4; HDAC6; HDAC8

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

OR52E2, CT (OR52E2, Olfactory receptor 52E2) (FITC) discontinued
039431-FITC 200 µL

OR52E2, CT (OR52E2, Olfactory receptor 52E2) (FITC) discontinued

Sign In for Pricing
View Details
POLR2H Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E10]
TA810781BM 100 µL

POLR2H Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E10]

Sign In for Pricing
View Details
Human PPARGC1A/Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ELISA Kit
E2005Hu 96 Tests

Human PPARGC1A/Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ELISA Kit

Sign In for Pricing
View Details
TNFSF13 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
bs-5725R-BF350 100 µL

TNFSF13 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Sign In for Pricing
View Details
Lentiviral mouse Igsf5 shRNA (UAS) - Lentiviral mouse Igsf5 shRNA (UAS) (100)
GTR15251994 1 Vial

Lentiviral mouse Igsf5 shRNA (UAS) - Lentiviral mouse Igsf5 shRNA (UAS) (100)

Sign In for Pricing
View Details
Recombinant Human PTGES2 CF
7627-PS-020 20 µg

Recombinant Human PTGES2 CF

Sign In for Pricing
View Details