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Laccase-IN-5

Laccase-IN-5 (Compound 2b) is the inhibitor for Laccase with an IC50 of 0.82 μM. Laccase-IN-5 increases the cell membrane permeability, limits the growth of hyphae, destorys the cell wall, and induces oxidative stress responses. Laccase-IN-5 exhibits antifungal activity against various plant pathogenic fungi and oomycetes, inhibits B. dothidea with an EC50 of 0.96 mg/L[1].

Product Specifications

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC(C)C1=CC=C(C(NNC2=CC=C(F)C=C2)=O)C=C1

Molecular Formula

C16H17FN2O

Molecular Weight

272.32

References & Citations

[1]Yang Z, et al., Design, Synthesis, and Antifungal Evaluation of Novel Cuminic Acid Derivatives as Potential Laccase Inhibitors. J Agric Food Chem. 2024 Dec 18;72 (50) :27726-27736.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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