E3 ligase Ligand 47
E3 ligase Ligand 47 is an E3 ligase ligand that can be used to synthesize PROTAC LDD39 (HY-159967) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
O=C(C(CC1)N(C2=O)CC(C=C3)=C2C=C3C(CC4)CCN4[C@@H](C5)C[C@@H]5C(O)=O)NC1=O
Molecular Formula
C23H27N3O5
Molecular Weight
425.48
References & Citations
[1]Qiao JX, et al. Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase. J Med Chem. 2024 Nov 14;67 (21) :19736-19754.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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