Antimicrobial agent-35

Antimicrobial agent-35 (Compound c9) exhibits antibacterial agent, that inhibits S. aureus, E. coli, E. faecalis, and S. maltophilia with MIC of 0.5-2 μg/mL. Antimicrobial agent-35 exhibits cytotoxicity against HT-22 with IC50 of 130.4 μg/mL[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC1=CC=CC(CNC[C@H]([C@@H](CC)OC(C[C@H]([C@@H]([C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]2O)[C@H](C[C@H]3C)CCN(CC4=CN(C5=CN=C(C=CC=C6)C6=C5)N=N4)C)C)O)=O)/C=C(C)/C=C/C3=O)=C1

Molecular Formula

C52H73N7O8

Molecular Weight

924.18

References & Citations

[1]Fan Z, et al., Design, Synthesis, and Activity Evaluation of C-23-Modified 5-O-Mycaminosyltylonolide Derivatives. ACS Med Chem Lett. 2024 Nov 25;15 (12) :2171-2180.