E3 Ligase Ligand-linker Conjugate 150
E3 Ligase Ligand-linker Conjugate 150 is the conjugate of the ligand for E3 ligase VHL and the linker, that can be used for synthesis of PROTAC SMARCA2 degrader-32.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)N(N=N4)C=C4[C@@H](CC5)CC[C@H]5C=O
Molecular Formula
C32H42N6O4S
Molecular Weight
606.78
References & Citations
[1]Li Z, et al., Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders. J Med Chem. 2024 Nov 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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