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SMARCA2 ligand-11

SMARCA2 ligand-11 is the ligand for SMARCA2, and can be used for synthesis of PROTAC SMARCA2 degrader-32 (HY-170343) as ligand for target protein[1].

Product Specifications

CAS Number

[3033592-44-5]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; SWI/SNF Complex

Related Pathways

Cell Cycle/DNA Damage; PROTAC

Field of Research

Cancer

Smiles

O=C1N=C2N(C3=CC(C4CCNCC4)=CC=C3C2(C)C)C5=C1C(Cl)=CC=C5

Molecular Formula

C22H22ClN3O

Molecular Weight

379.88

References & Citations

[1]Li Z, et al., Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders. J Med Chem. 2024 Nov 21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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