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ZCL279

ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction. ZCL279 can activate Cdc42 (a cytoplasmic small GTPase in the Ras superfamily) at lower concentrations ([1].

Product Specifications

CAS Number

664975-73-9

UNSPSC

12352005

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Purity

99.2

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=CC=C1NS(=O)(C2=CC=C(OC3=C4C=C(S(=O)(NC5=C(O)C=CC=C5)=O)C=C3)C4=C2)=O

Molecular Formula

C24H18N2O7S2

Molecular Weight

510.54

References & Citations

[1]Malasala S, et al. Enabling Systemic Identification and Functionality Profiling for Cdc42 Homeostatic Modulators. bioRxiv [Preprint]. 2024 Jan 8:2024.01.05.574351.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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