TDO2-IN-1
TDO2-IN-1 (Cpd-2) is a potent inhibitor of Human TDO2, with the IC50 of 14.8 nM. TDO2-IN-1 plays an important role in metabolism, inflammation, and tumor immune surveillance research[1].
Product Specifications
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C1N2C(C(N([C@@H](C)C3=CC=CC=C3)C(NC4=CC=CC=C4C(C)C)=O)CCC2)=NC(OC)=C1C(OCC)=O
Molecular Formula
C30H36N4O5
Molecular Weight
532.63
References & Citations
[1]Carina Lotz-Jenne, et al. Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2. Sci Rep. 2024 Nov 14;14 (1) :27937.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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