CMP233
CMP233 is a potent antagonist of TRPM4, with the IC50 of 0.15 μM. CMP233 plays an important role in neurodegenerative disorders research[1].
Product Specifications
CAS Number
[307001-06-5]
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(O)C1=CC(Br)=CC=C1NC(CCC2=CC=CC=C2)=O
Molecular Formula
C16H14BrNO3
Molecular Weight
348.19
References & Citations
[1]Lars Binkle-Ladisch, et al. Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity. iScience. 2024 Nov 19;27 (12) :111425.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPM8
Curated Selection
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