Oseltamivir-13C, d3 (phosphate)

Oseltamivir-13C, d3 (phosphate) (GS 4104-13C, d3 (phosphate) ) is 13C labeled Oseltamivir (phosphate) . Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.

Product Specifications

CAS Number

[2734920-81-9]

Product Name Alternative

GS 4104-13C, d3 (phosphate)

UNSPSC

12352211

Target

Influenza Virus; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection; Cancer

Smiles

O=P(O)(O)O.CCC(O[C@H]1[C@H](NC([13C]([2H])([2H])[2H])=O)[C@@H](N)CC(C(OCC)=O)=C1)CC

Molecular Formula

C15 13CH28D3N2O8P

Molecular Weight

414.41

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Huang H, et al. Transplacental transfer of Oseltamivir phosphate and its metabolite Oseltamivir carboxylate using the ex vivo human placenta perfusion model in Chinese Hans population. J Matern Fetal Neonatal Med. 2016 Aug 8:1-5.|[3]de Oliveira JT, et al. Anti-influenza neuraminidase inhibitor Oseltamivir phosphate induces canine mammary cancer cell aggressiveness. PLoS One. 2015 Apr 7;10 (4) :e0121590.|[4]Li P, et al. A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase. Viruses. 2018 Jun 13;10 (6) . pii: E325.