9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Maleate
9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Maleate is the deuterium labeled CRBN ligand-74. CRBN ligand-74 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
Product Specifications
CAS Number
1219806-48-0
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Ligands for E3 Ligase
Related Pathways
Others; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC(/C=C/C(O)=O)=O.NC1=C2C(CCC([2H])([2H])C2([2H])O)=NC3=CC=CC=C31
Molecular Formula
C17H15D3N2O5
Molecular Weight
333.35
References & Citations
[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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