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CRBN ligand-12

CRBN ligand-12 (Compound 9) is a CRBN-type E3 ubiquitin ligase ligand. CRBN ligand-12 can be used to prepare PROTACs[1].

Product Specifications

CAS Number

[2820501-20-8]

UNSPSC

12352005

Target

E1/E2/E3 Enzyme; Ligands for E3 Ligase

Related Pathways

Metabolic Enzyme/Protease; PROTAC

Field of Research

Cancer

Smiles

O=C(C(C1=C(F)C=C(N2CC(CO)C2)C=C1F)CC3)NC3=O

Molecular Formula

C15H16F2N2O3

Molecular Weight

310.30

References & Citations

[1]lei, et al. (R) -Glutarimide CRBN ligand and methods of use. CN117616021A. China. 2022-06-21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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