CRBN ligand-12
CRBN ligand-12 (Compound 9) is a CRBN-type E3 ubiquitin ligase ligand. CRBN ligand-12 can be used to prepare PROTACs[1].
Product Specifications
CAS Number
[2820501-20-8]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme; Ligands for E3 Ligase
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
O=C(C(C1=C(F)C=C(N2CC(CO)C2)C=C1F)CC3)NC3=O
Molecular Formula
C15H16F2N2O3
Molecular Weight
310.30
References & Citations
[1]lei, et al. (R) -Glutarimide CRBN ligand and methods of use. CN117616021A. China. 2022-06-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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