XJ5
XJ5 is a non-nucleoside covalent inhibitor of Nsp12 (IC50=0.12 μM), which is the non-structural protein 12 of the virus. XJ5 has the potential to be an antiviral inhibitor of SARS-CoV-2[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
BrC1=CC=C(CN(CC(O)=O)C2=NC(Cl)=CC(N3CCN(C(CCl)=O)CC3)=N2)C(N4CCOCC4)=C1
Molecular Formula
C23H27BrCl2N6O4
Molecular Weight
602.31
References & Citations
[1]Wang X, et al. Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors. J Am Chem Soc. 2024 Dec 11;146 (49) :33983-33996.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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