CK2-IN-13
CK2-IN-13 (compound 12c) is a potent inhibitor of CK2, with the IC50 of 5.8 nM. CK2-IN-13 plays an important role in cancer research[1].
Product Specifications
UNSPSC
12352101
Target
Casein Kinase
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(/C1=C\NC2=CC=CC=C2)CCC3=C1OC4=CC(Br)=C(O)C(Br)=C34
Molecular Formula
C19H13Br2NO3
Molecular Weight
463.12
References & Citations
[1]Hendrik Rumler, et al. Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthesis, Biological Evaluation, and Structural Studies on E-/Z-Isomers. ACS Pharmacol Transl Sci. 2024 Nov 19;7 (12) :3846-3866.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2
Curated Selection
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