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Succinate dehydrogenase-IN-4

Succinate dehydrogenase-IN-4 (Compound 4b) is the inhibitor for succinate dehydrogenase with an IC50 of 3.38 μM. Succinate dehydrogenase-IN-4 exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare with EC50 of 16.33 μM and 18.06 μM[1].

Product Specifications

UNSPSC

12352005

Target

Succinate Dehydrogenase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

CC1=CC[C@@H](C(CSC2=NN=C(NC(C3=CC=CC=C3C)=O)S2)=C)CC1=O

Molecular Formula

C20H21N3O2S2

Molecular Weight

399.53

References & Citations

[1]Li B, et al., Synthesis and Antifungal Activity Evaluation of Novel L-Carvone-Based 1,3,4-Thiadiazole-amide Derivatives as a Potential Succinate Dehydrogenase Inhibitor. J Agric Food Chem. 2024 Nov 27;72 (47) :26116-26124.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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