TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) is a dual modulator for mitochondrial translocator protein and Carbonic Anhydrase with a Ki of 1.340 μM for TSPO and a KA of 10.7 μM for CA VII. TSPO/Carbonic Anhydrase Modulator 1 promotes the production of neurosteroid, increases BDNF gene expression, exhibits neuroprotective efficacy[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Smiles
CN(C(C1=CC=CC=C1)=C2C(C(N(CCCCCC)CCCCCC)=O)=O)C3=C2C=C(OCCN(CC)CC)C=C3
Molecular Formula
C35H51N3O3
Molecular Weight
561.80
References & Citations
[1]Poggetti V, et al., Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity. ACS Chem Neurosci. 2025 Jan 1;16 (1) :1-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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