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TSPO/Carbonic Anhydrase Modulator 1

TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) is a dual modulator for mitochondrial translocator protein and Carbonic Anhydrase with a Ki of 1.340 μM for TSPO and a KA of 10.7 μM for CA VII. TSPO/Carbonic Anhydrase Modulator 1 promotes the production of neurosteroid, increases BDNF gene expression, exhibits neuroprotective efficacy[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

CN(C(C1=CC=CC=C1)=C2C(C(N(CCCCCC)CCCCCC)=O)=O)C3=C2C=C(OCCN(CC)CC)C=C3

Molecular Formula

C35H51N3O3

Molecular Weight

561.80

References & Citations

[1]Poggetti V, et al., Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity. ACS Chem Neurosci. 2025 Jan 1;16 (1) :1-15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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