BChE-IN-38

BChE-IN-38 (compound 13) is a potent BChE inhibitor with Ki values of 62.05, 28.78, 14.09, 1.15 nM for hCAI, hCAII, AChE, BChE, respectively. BChE-IN-38 shows cytotoxic activity[1].

Product Specifications

CAS Number

[3054159-55-3]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

N1(CC2=CN(C3=C4C(C=CC=C4)=CC=C3)N=N2)C5=CC=CC=C5C=CC6=CC=CC=C61

Molecular Formula

C27H20N4

Molecular Weight

400.47

References & Citations

[1]Erdoğan M, et al. Novel Dibenzoazepine-Substituted Triazole Hybrids as Cholinesterase and Carbonic Anhydrase Inhibitors and Anticancer Agents: Synthesis, Characterization, Biological Evaluation, and In Silico Studies. ACS Omega. 2024 Nov 16;9 (47) :46860-46878.