ROS-ERS inducer 2
ROS-ERS inducer 2 (Complex 3f) triggers intracellular ROS generation and affect the function of mitochondria. promote the release of damage-associated molecular patterns (DAMPs), induce immunogenic cell death (ICD) and activates endoplasmic reticulum stress (ERS) . ROS-ERS inducer 2 plays an important role in anti-liver cancer research[1].
Product Specifications
CAS Number
3081736-89-9
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
FC1=CC=C(C2=C(N(CC)[C-2](N2CC)=[Pt+4]([Br-])([N]3=CC=CC=C3)[Cl-])C4=CC=C(C=C4)F)C=C1
Molecular Formula
C24H23BrClF2N3Pt
Molecular Weight
701.90
References & Citations
[1]Lu Tang, et al. More than just DNA damage: Pt (ΙΙ) -NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death. Eur J Med Chem. 2025 Jan 15:282:117014.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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