ROS-ERS inducer 2

ROS-ERS inducer 2 (Complex 3f) triggers intracellular ROS generation and affect the function of mitochondria. promote the release of damage-associated molecular patterns (DAMPs), induce immunogenic cell death (ICD) and activates endoplasmic reticulum stress (ERS) . ROS-ERS inducer 2 plays an important role in anti-liver cancer research[1].

Product Specifications

CAS Number

[3081736-89-9]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

FC1=CC=C(C2=C(N(CC)[C-2](N2CC)=[Pt+4]([Br-])([N]3=CC=CC=C3)[Cl-])C4=CC=C(C=C4)F)C=C1

Molecular Formula

C24H23BrClF2N3Pt

Molecular Weight

701.90

References & Citations

[1]Lu Tang, et al. More than just DNA damage: Pt (ΙΙ) -NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death. Eur J Med Chem. 2025 Jan 15:282:117014.