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CRBN ligand-10

CRBN ligand-10 (compound 18) is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(C(C1=CC=CC2=C1C=CN2)CC3)NC3=O

Molecular Formula

C13H12N2O2

Molecular Weight

228.25

References & Citations

[1]Zhou Y, et al. Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery. ACS Med Chem Lett. 2024 Nov 15;15 (12) :2158-2163.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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