CRBN ligand-10
CRBN ligand-10 (compound 18) is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC[1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(C(C1=CC=CC2=C1C=CN2)CC3)NC3=O
Molecular Formula
C13H12N2O2
Molecular Weight
228.25
References & Citations
[1]Zhou Y, et al. Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery. ACS Med Chem Lett. 2024 Nov 15;15 (12) :2158-2163.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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