APOL1-IN-2
APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1) . APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively[1].
Product Specifications
CAS Number
2956781-84-1
UNSPSC
12352005
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(N1[C@@H]2C[C@](C)(O)C2)N(CO)C3=C1C(C(F)(F)F)=CC(OCCN(CC4)CCC4(C(N5)=O)C6=C5C=CC(Cl)=C6)=C3
Molecular Formula
C28H30ClF3N4O5
Molecular Weight
595.01
References & Citations
[1]Lee PST, et al., APOL1 inhibitors and methods of use. US11976067B2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
247106-ML750 100 µL
HLA-DMB (Major Histocompatibility Complex, Class II, DM beta, D6S221E, RING7) (MaxLight 750) discontinued
Sign In for Pricing
View Details 
MBS452126-01 48 Tests
Human Ferritin, Light Polypeptide (FTL) ELISA Kit
Sign In for Pricing
View Details MBS452126-02 96 Tests
Human Ferritin, Light Polypeptide (FTL) ELISA Kit
Sign In for Pricing
View Details MBS452126-03 5x 96 Tests
Human Ferritin, Light Polypeptide (FTL) ELISA Kit
Sign In for Pricing
View Details MBS452126-04 10x 96 Tests
Human Ferritin, Light Polypeptide (FTL) ELISA Kit
Sign In for Pricing
View Details orb1516620-01 20 µg
Recombinant human LH Alpha / Beta Heterodimer protein, C-His (HEK293)
Sign In for Pricing
View Details