CDK2 degrader 5
CDK2 degrader 5 (compound 12) is a degrader for CDK2, with the Dmax of >50% and ≤80% in HiBiT Assay. CDK2 degrader 5 plays an important role in cancer research[1].
Product Specifications
CAS Number
[2923574-11-0]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.17
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=C2C(C(N(C3C(NC(CC3)=O)=O)C2)=O)=C1)OCC4=CC=CC(C5=CC=CC=C5)=C4C
Molecular Formula
C29H27N3O5
Molecular Weight
497.54
References & Citations
[1]Monte Rosa Therapeutics, Inc. Preparation of 3- (6-substituted-1-oxoisoindolin-2-yl) piperidine-2,6-dione derivatives that mediate the degradation of cyclin-dependent kinase (CDK2) and are useful in the treatment of various disorders, such as cancer. World Intellectual Property Organization, WO2023069700 A1 2023-04-27
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
Available Sizes
Curated Selection
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