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STAT3-IN-37

STAT3-IN-37 (Compound 101) is the inhibitor for STAT3 with an IC50 of 15 nM (measuring by DNA-HTRF assay) or 2 nM (measuring by human whole blood SOCS3 qPCR assay) [1].

Product Specifications

CAS Number

[3055844-98-6]

UNSPSC

12352005

Target

STAT

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C1NN=CC(CCCN2CC3(CC(C3)CC(C=CC(Cl)=C45)=C5C=NN(C)C4=O)C2)=C1Cl

Molecular Formula

C23H25Cl2N5O2

Molecular Weight

474.38

References & Citations

[1]Wu Q, et al., 2-azaspiro[3.3]heptane derivatives as stat3 inhibitors for the treatment of cancer. WO2024182693A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

STAT3

Available Sizes

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