STAT3-IN-37
STAT3-IN-37 (Compound 101) is the inhibitor for STAT3 with an IC50 of 15 nM (measuring by DNA-HTRF assay) or 2 nM (measuring by human whole blood SOCS3 qPCR assay) [1].
Product Specifications
CAS Number
[3055844-98-6]
UNSPSC
12352005
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1NN=CC(CCCN2CC3(CC(C3)CC(C=CC(Cl)=C45)=C5C=NN(C)C4=O)C2)=C1Cl
Molecular Formula
C23H25Cl2N5O2
Molecular Weight
474.38
References & Citations
[1]Wu Q, et al., 2-azaspiro[3.3]heptane derivatives as stat3 inhibitors for the treatment of cancer. WO2024182693A1.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169908/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3
Available Sizes
Curated Selection
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