STAT3-IN-37
STAT3-IN-37 (Compound 101) is the inhibitor for STAT3 with an IC50 of 15 nM (measuring by DNA-HTRF assay) or 2 nM (measuring by human whole blood SOCS3 qPCR assay) [1].
Product Specifications
CAS Number
3055844-98-6
UNSPSC
12352005
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1NN=CC(CCCN2CC3(CC(C3)CC(C=CC(Cl)=C45)=C5C=NN(C)C4=O)C2)=C1Cl
Molecular Formula
C23H25Cl2N5O2
Molecular Weight
474.38
References & Citations
[1]Wu Q, et al., 2-azaspiro[3.3]heptane derivatives as stat3 inhibitors for the treatment of cancer. WO2024182693A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3
Available Sizes
Frequently Asked Questions
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