AS2690168 (freebase)
AS2690168 freebase is an orally active RANKL signal transduction inhibitor which suppresses RANKL-induced osteoclastogenesis of RAW264 cells. AS2690168 can be utilized in research related to pathological osteolysis[1].
Product Specifications
CAS Number
[1393999-78-4]
UNSPSC
12352005
Target
RANKL/RANK
Related Pathways
NF-κB
Field of Research
Others
Smiles
FC1=CC(F)=C(CNC2=C(OC)C=NC(C3=NC=CC=C3)=N2)C(F)=C1
Molecular Formula
C17H13F3N4O
Molecular Weight
346.31
References & Citations
[1]Morikawa N, et al. Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor. Eur J Pharmacol. 2022 Jun 5;924:174941.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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